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KMID : 0604020160310020162
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Korean Journal of Critical Care Medicine
2016 Volume.31 No. 2 p.162 ~ p.168
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Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome following HAART Initiation in an HIV-infected Patient Being Treated for Severe Pneumocystis jirovecii Pneumonia: Case Report and Literature Review
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Park Dong-Won
Lim Dae-Hyun
Kim Bong-Young
Yhi Ji-Young
Moon Ji-Yong
Kim Sang-Heon
Kim Tae-Hyung
Shon Jang-Won
Yoon Ho-Joo
Shin Dong-Ho
Pai Hyun-Joo
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Abstract
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Pnuemocystis jirovecii pneumonia (PJP) is one of leading causes of acute respiratory failure in patients infected with human immunodeficiency virus (HIV), and the mortality rate remains high in mechanically ventilated HIV patients with PJP. There are several reported cases who received extracorporeal membrane oxygenation (ECMO) treatment for respiratory failure associated with severe PJP in HIV-infected patients. We report a patient who was newly diagnosed with HIV and PJP whose condition worsened after highly active antiretroviral therapy (HAART) initiation and progressed to acute respiratory distress syndrome requiring veno-venous ECMO. The patient recovered from PJP and is undergoing treatment with HAART. ECMO support can be an effective life-saving salvage therapy for acute respiratory failure refractory to mechanical ventilation following HAART in HIV-infected patients with severe PJP.
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KEYWORD
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extracorporeal membrane oxygenation, HIV, Pneumocystis jirovecii, respiratory failure
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